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KMID : 0613820120220070943
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Journal of Life Science
2012 Volume.22 No. 7 p.943 ~ p.949
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Charactrization of Biological Activities of Rehmannia glutinosa Extracts
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Cho Young-Je
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Abstract
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The content phenolic compounds in extracts from Rehmannia glutinosa was the highest in 40% ethanol extracts as 5.1±0.2mg/g. DPPH scavenging activity of R. glutinosa extracts was high in water extracts and 40% ethanol extracts as 85~93%, ABTS radical cation decolorization of water extracts and 40% ethanol extracts was about the same as 55~62%, antioxidant protection factor (PF) was confirmed in water extracts and 40% ethanol extracts as 1.6~1.9 PF, and TBARs of water extracts and 40% ethanol extracts were concluded to have the similar antioxidant effects. The hypertension inhibitory activity of water extracts and 40% ethanol extracts from R. glutinosa indicated the activities as 87.2% and 81.1%, anti-gout activity was determined very low in R. glutinosa extracts and antimicrobial activity against skin microorgasm was confirmed, and tyrosinase inhibitory activity was determined as 70.2% in 40% ethanol extracts, it was expected the whitening effects in 40% ethanol extracts. The elastase inhibitory activity which are related to the wrinkle cause was observed in water extracts and 40% ethanol extracts as 76.2% and 57.2%. The hyaluronidase inhibitory activity to R. glutinosa extracts was observed weakly in only 40% ethanol extracts of 200μg/ml phenolic content as 5.1%.
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KEYWORD
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Biological activities, functional food, functional cosmetic, Rehmannia glutinosa
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